Who Owns KARYOPHARM THERAPEUTICS INC (KPTI)? -- Institutional Holders (2026-06-30)

116 institutions reported holding $225.1M of KARYOPHARM THERAPEUTICS INC (KPTI) in SEC 13F filings for 2026-06-30. Largest institutional holders: RA CAPITAL MANAGEMENT, L.P. ($18.7M), ADAGE CAPITAL PARTNERS GP, L.L.C. ($14.9M), ACORN CAPITAL ADVISORS, LLC ($14.8M), GOLDMAN SACHS GROUP INC ($13.9M), BlackRock, Inc. ($13.9M). Source: SEC Form 13F.

Rank	Institution	Value	Shares	Change
1	RA CAPITAL MANAGEMENT, L.P.	$18.7M	1.9M	Hold
2	ADAGE CAPITAL PARTNERS GP, L.L.C.	$14.9M	1.5M	Trimmed
3	ACORN CAPITAL ADVISORS, LLC	$14.8M	1.5M	Added
4	GOLDMAN SACHS GROUP INC	$13.9M	1.4M	Added
5	BlackRock, Inc.	$13.9M	1.4M	Added
6	VANGUARD GROUP INC	$12.2M	1.2M	Added
7	Catalio Capital Management, LP	$9.2M	940,855	Added
8	Avidity Partners Management LP	$9.0M	924,487	Added
9	T. Rowe Price Investment Management, Inc.	$7.7M	786,309	Trimmed
10	TWO SIGMA INVESTMENTS, LP	$6.8M	695,264	Added
11	Kalehua Capital Management LLC	$6.7M	685,644	New
12	NEA Management Company, LLC	$5.6M	576,780	New
13	SUSQUEHANNA INTERNATIONAL GROUP, LLP	$5.3M	545,700	Trimmed
14	GEODE CAPITAL MANAGEMENT, LLC	$5.2M	531,231	Added
15	Ghisallo Capital Management LLC	$4.9M	500,000	New
16	Soleus Capital Management, L.P.	$4.3M	440,000	Hold
17	Caption Management, LLC	$3.7M	378,200	Trimmed
18	UBS Group AG	$3.5M	353,545	Added
19	MILLENNIUM MANAGEMENT LLC	$3.3M	341,676	Trimmed
20	STATE STREET CORP	$3.2M	325,991	Added
21	Affinity Asset Advisors, LLC	$3.1M	312,500	Trimmed
22	Brevan Howard Capital Management LP	$3.0M	309,817	Added
23	Boxer Capital Management, LLC	$3.0M	302,536	Hold
24	Davidson Kempner Capital Management LP	$2.9M	300,000	Hold
25	ACADIAN ASSET MANAGEMENT LLC	$2.9M	298,997	Added

Source: SEC Form 13F filings · as of 2026-06-30